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A NATIONAL PROBLEM
who has to send the prescription to the pharmacy every month. Due to insur- ance restrictions, the medication is only available in one-month supplies and can only be lled when a patient is about one day from running out—a small time frame that can be further compounded in the midst of an Adder- all shortage, she said. “It’s just been a crazy rat race,” Ramagos said. “You can’t call [your prescription] in until you’re almost out, and then the pharmacy can’t get it so then you may be out of medicine for three or four days, a week [or] two weeks.” The Ramagos family is one of many who have been dealing with the same struggle since the Food and Drug Administration added Adderall to its shortage list on Oct. 10, according to the agency’s website. Beyond Adderall, widespread drug shortages have been seen across the U.S. since the fall, leaving Spring- and Klein-area patients as well as medical personnel scrambling to meet their needs. Ongoing shortages At the end of the rst quarter of this FOLLOWING THE SUPPLY CHAIN
Nationally, drug shortages peaked in the rst quarter of 2023 at 301, compared to the previous ve years, according to a national study conducted by the University of Utah Drug Information Service.
Number of drug shortages nationally by quarter
301
300 350 250 50 100 150 200
276
276
271
242
202
0
Q1
Q2 Q3 Q4
Q1
Q2
Q3
Q4
Q1
Q2 Q3 Q4
Q1
Q2
Q3
Q4 Q1
Q2 Q3 Q4 Q1
2018
2019
2020
2021
2022
2023
SOURCES: UNIVERSITY OF UTAH DRUG INFORMATION SERVICE, AMERICAN SOCIETY OF HOSPITAL PHARMACISTSCOMMUNITY IMPACT
year, 301 drug shortages were ongoing, according to a national report from the University of Utah Drug Information Service. This represents a 23% increase in drug shortages from one year ago. Ongoing and active drug shortages are the most numerous they’ve been since 2014, according to the report. “Right now, we can only get a certain
amount [of medication] every month, so we can ll some patients’ [prescrip- tions], but we can’t ll everything,” said Tracy Ngo, a pharmacist at Light- house Pharmacy in Spring. “I’d say it’s aecting 20%-30% of our patients.” Beginning in October, some of the biggest drug shortages in addition to Adderall have been Albuterol, an
asthma medication, and Ozempic, a diabetes medication, said Dr. Joshua Wollen, a clinical assistant professor at the University of Houston’s pharmacy practice and translation research department. “Those big three—Albuterol, Adder- all and Ozempic—are probably the most pronounced ones because
Multiple parties—such as suppliers, manufacturers, wholesalers, hospitals and pharmacies— make up the supply chain for medications, according to the Food and Drug Administration, and disruptions can happen at any point along the journey, causing drug shortages.
Pharmacy or hospital
Wholesaler distributor (primary)
Supplier : Provides components and ingredients for medications to manufacturers
Manufacturer : Processes ingredients for pharmaceutical products
Manufacturer
Supplier
Patient
Wholesaler distributor : Purchases medications from manufacturers and distributes them to customers; independent pharmacies can seek out secondary wholesaler distributors when looking for out-of-stock medications
Repackager : Moves medications into dierent containers without altering the product
Pharmacy or hospital : Can also include nursing homes, doctor’s oces, labs and clinics
Patient : 48.6% of people in the U.S. used a prescription drug in the last 30 days from 2015-18.
Wholesaler distributor (secondary)
Repackager
SOURCES: FOOD AND DRUG ADMINISTRATION, U.S. ENVIRONMENTAL PROTECTION AGENCY, THE KAISER FAMILY FOUNDATION, CENTERS FOR DISEASE CONTROL AND PREVENTIONCOMMUNITY IMPACT
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